Structural and Mutational Studies of a Hyperthermophilic Intein from DNA Polymerase II of Pyrococcus abyssi

Protein splicing is a precise self-catalyzed process in which an intein excises itself from a precursor with the concomitant ligation of the flanking polypeptides (exteins). Protein splicing proceeds through a four-step reaction but the catalytic mechanism is not fully understood at the atomic level...

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Main Authors: Du, Zhenming, Liu, Jiajing, Albracht, Clayton D., Hsu, Alice, Chen, Wen, Marieni, Michelle D., Colelli, Kathryn M., Williams, Jennie E., Reitter, Julie N., Mills, Kenneth V., Wang, Chunyu
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Protein Structure and Folding
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207444/
https://ncbi.nlm.nih.gov/pubmed/21914805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.290569
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