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T Cell Activation by Terminal Complex of Complement and Immune Complexes

T cell hyperactivation and complement consumption are prominent features of the immunopathology of systemic lupus erythematosus. Although complement activation is secondary to autoantibodies that form immune complexes (ICs), the trigger for alterations in human peripheral blood T cells is poorly und...

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Autori principali: Chauhan, Anil K., Moore, Terry L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207419/
https://ncbi.nlm.nih.gov/pubmed/21900254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.266809
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