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Premature Activation of the Paramyxovirus Fusion Protein before Target Cell Attachment with Corruption of the Viral Fusion Machinery

Paramyxoviruses, including the childhood pathogen human parainfluenza virus type 3, enter host cells by fusion of the viral and target cell membranes. This fusion results from the concerted action of its two envelope glycoproteins, the hemagglutinin-neuraminidase (HN) and the fusion protein (F). The...

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Autori principali: Farzan, Shohreh F., Palermo, Laura M., Yokoyama, Christine C., Orefice, Gianmarco, Fornabaio, Micaela, Sarkar, Aurijit, Kellogg, Glen E., Greengard, Olga, Porotto, Matteo, Moscona, Anne
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207398/
https://ncbi.nlm.nih.gov/pubmed/21799008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.256248
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