Premature Activation of the Paramyxovirus Fusion Protein before Target Cell Attachment with Corruption of the Viral Fusion Machinery

Paramyxoviruses, including the childhood pathogen human parainfluenza virus type 3, enter host cells by fusion of the viral and target cell membranes. This fusion results from the concerted action of its two envelope glycoproteins, the hemagglutinin-neuraminidase (HN) and the fusion protein (F). The...

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Detalhes bibliográficos
Main Authors: Farzan, Shohreh F., Palermo, Laura M., Yokoyama, Christine C., Orefice, Gianmarco, Fornabaio, Micaela, Sarkar, Aurijit, Kellogg, Glen E., Greengard, Olga, Porotto, Matteo, Moscona, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207398/
https://ncbi.nlm.nih.gov/pubmed/21799008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.256248
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