Distinct Hydration Properties of Wild-Type and Familial Point Mutant A53T of α-Synuclein Associated with Parkinson's Disease

The propensity of α-synuclein to form amyloid plays an important role in Parkinson's disease. Three familial mutations, A30P, E46K, and A53T, correlate with Parkinson's disease. Therefore, unraveling the structural effects of these mutations has basic implications in understanding the mole...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Hazy, E., Bokor, M., Kalmar, L., Gelencser, A., Kamasa, P., Han, K.-H., Tompa, K., Tompa, P.
Формат: Artigo
Язык:Inglês
Опубликовано: The Biophysical Society 2011
Предметы:
Protein
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207174/
https://ncbi.nlm.nih.gov/pubmed/22067166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.08.052
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы