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Nucleolar protein Spindlin1 recognizes H3K4 methylation and stimulates the expression of rRNA genes

The tandem Tudor-like domain-containing protein Spindlin1 has been reported to be a meiotic spindle-associated protein. Here we report that Spindlin1 is not associated with the spindle in mouse embryonic fibroblast cells during mitotic divisions. In interphase cells, Spindlin1 specifically localizes...

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Detalhes bibliográficos
Main Authors: Wang, Weixiang, Chen, Zhi, Mao, Zhuo, Zhang, Huihui, Ding, Xiaojun, Chen, She, Zhang, Xiaodong, Xu, Ruiming, Zhu, Bing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207104/
https://ncbi.nlm.nih.gov/pubmed/21960006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.184
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