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miRNA screening reveals a new miRNA family stimulating iPS cell generation via regulation of Meox2

Induced pluripotent stem cells (iPSCs) can be generated by overexpression of Oct4, Sox2 and Klf4 in murine fibroblasts. By conducting a microRNA (miRNA) library screen, we identified a set of miRNAs critically regulating iPSC formation. We revealed a new miRNA family (miR-130/301/721) as an importan...

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Bibliografische gegevens
Hoofdauteurs: Pfaff, Nils, Fiedler, Jan, Holzmann, Angelika, Schambach, Axel, Moritz, Thomas, Cantz, Tobias, Thum, Thomas
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207101/
https://ncbi.nlm.nih.gov/pubmed/21941297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.176
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