miRNA screening reveals a new miRNA family stimulating iPS cell generation via regulation of Meox2

Induced pluripotent stem cells (iPSCs) can be generated by overexpression of Oct4, Sox2 and Klf4 in murine fibroblasts. By conducting a microRNA (miRNA) library screen, we identified a set of miRNAs critically regulating iPSC formation. We revealed a new miRNA family (miR-130/301/721) as an importan...

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Detalhes bibliográficos
Main Authors: Pfaff, Nils, Fiedler, Jan, Holzmann, Angelika, Schambach, Axel, Moritz, Thomas, Cantz, Tobias, Thum, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207101/
https://ncbi.nlm.nih.gov/pubmed/21941297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.176
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