miRNA screening reveals a new miRNA family stimulating iPS cell generation via regulation of Meox2

Induced pluripotent stem cells (iPSCs) can be generated by overexpression of Oct4, Sox2 and Klf4 in murine fibroblasts. By conducting a microRNA (miRNA) library screen, we identified a set of miRNAs critically regulating iPSC formation. We revealed a new miRNA family (miR-130/301/721) as an importan...

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Bibliographic Details
Main Authors: Pfaff, Nils, Fiedler, Jan, Holzmann, Angelika, Schambach, Axel, Moritz, Thomas, Cantz, Tobias, Thum, Thomas
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2011
Subjects:
Scientific Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207101/
https://ncbi.nlm.nih.gov/pubmed/21941297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.176
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