Apoptotic Effects of Genistein, Biochanin-A and Apigenin on LNCaP and PC-3 Cells by p21 through Transcriptional Inhibition of Polo-like Kinase-1

Natural isoflavones and flavones are important dietary factors for prostate cancer prevention. We investigated the molecular mechanism of these compounds (genistein, biochanin-A and apigenin) in PC-3 (hormone-independent/p53 mutant type) and LNCaP (hormone-dependent/p53 wild type) prostate cancer ce...

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Detalhes bibliográficos
Main Authors: Seo, Young Jin, Kim, Bum Soo, Chun, So Young, Park, Yoon Kyu, Kang, Ku Seong, Kwon, Tae Gyun
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Academy of Medical Sciences 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207053/
https://ncbi.nlm.nih.gov/pubmed/22065906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3346/jkms.2011.26.11.1489
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