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TLR2 agonist PSK activates human NK cells and enhances the anti-tumor effect of HER2-targeted monoclonal antibody therapy

PURPOSE: The therapeutic effect of trastuzumab monoclonal antibody (mAb) therapy has been shown to be partially dependent on functional NK cells. Novel agents that enhance NK cell function could potentially improve the anti-tumor effect of trastuzumab. We recently identified polysaccharide krestin (...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lu, Hailing, Yang, Yi, Gad, Ekram, Inatsuka, Carol, Wenner, Cynthia A., Disis, Mary L., Standish, Leanna J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206987/
https://ncbi.nlm.nih.gov/pubmed/21918170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-1142
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