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DPO multiplex PCR as an alternative to culture and susceptibility testing to detect Helicobacter pylori and its resistance to clarithromycin

BACKGROUND: Macrolide resistance in Helicobacter pylori is the major risk factor for treatment failure when using a proton pump inhibitor-clarithromycin containing therapy. Macrolide resistance is due to a few mutations on the 23S ribomosal subunit encoded by the 23S rRNA gene. The present study aim...

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Detalhes bibliográficos
Main Authors: Lehours, Philippe, Siffré, Elodie, Mégraud , Francis
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206832/
https://ncbi.nlm.nih.gov/pubmed/22004003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-11-112
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