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Studies on deoxyribonucleic acids and related compounds. V. Synthesis of pentadecanucleotide duplex containing the ideal Pribnow sequence of promoter by the phosphotriester method using a new phosphorylating reagent.

A phosphorylating reagent o-chlorophenyl phosphoro-p-anisi-dochloridate was synthesized to phosphorylate the 3'-hydroxyl group of N, 5'-protected deoxynucleosides. These nucleotides served as 3'-terminal units for the synthesis of oligonucleotide blocks. By condensation of these oligo...

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Detalhes bibliográficos
Main Authors: Ohtsuka, E, Taniyama, Y, Marumoto, R, Sato, H, Hirosaki, H, Ikehara, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1982
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC320636/
https://ncbi.nlm.nih.gov/pubmed/7079181
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