Antibody responses and cross protection against lethal influenza A viruses differ between the sexes in C57BL/6 Mice

A mouse model was used to determine if protective immunity to influenza A virus infection differs between the sexes. The median lethal dose of H1N1 or H3N2 was lower for naïve females than males. After a sublethal, primary infection with H1N1 or H3N2, females and males showed a similar transient mor...

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Bibliographic Details
Main Authors: Lorenzo, Maria E., Hodgson, Andrea, Robinson, Dionne P., Kaplan, Jenifer B., Pekosz, Andrew, Klein, Sabra L.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206291/
https://ncbi.nlm.nih.gov/pubmed/21983155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.09.110
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