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Biological sex affects vaccine efficacy and protection against influenza in mice

Biological sex affects adaptive immune responses, which could impact influenza infection and vaccine efficacy. Infection of mice with 2009 H1N1 induced antibody responses, CD4(+) T cell and CD8(+) T cell memory responses that were greater in females than males; both sexes, however, were equally prot...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Fink, Ashley L., Engle, Kyrra, Ursin, Rebecca L., Tang, Wan-Yee, Klein, Sabra L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6298067/
https://ncbi.nlm.nih.gov/pubmed/30455317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1805268115
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