Muscle cells and motoneurons differentially remove mutant SOD1 causing familial amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal motoneuronal disease which occurs in sporadic or familial forms, clinically indistinguishable. About 15% of familial ALS cases are linked to mutations of the superoxide dismutase 1 (SOD1) gene that may induce misfolding in the coded protein, exerting ne...

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Detaylı Bibliyografya
Asıl Yazarlar: Onesto, Elisa, Rusmini, Paola, Crippa, Valeria, Ferri, Nicola, Zito, Arianna, Galbiati, Mariarita, Poletti, Angelo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Publishing Ltd 2011
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206220/
https://ncbi.nlm.nih.gov/pubmed/21554318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2011.07298.x
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