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Differential Contributions of Monocyte- and Platelet-derived Microparticles towards Thrombin Generation and Fibrin Formation and Stability

INTRODUCTION: Microparticles (MPs) are submicron vesicles shed by activated or apoptotic cells, including platelets and monocytes. Increased circulating MPs are associated with thrombosis; however, their role in thrombogenesis is poorly understood. OBJECTIVE: To determine how MPs promote thrombin ge...

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Detalhes bibliográficos
Main Authors: Aleman, Maria M., Gardiner, Chris, Harrison, Paul, Wolberg, Alisa S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206146/
https://ncbi.nlm.nih.gov/pubmed/21883880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2011.04488.x
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