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Angiogenin inhibits nuclear translocation of apoptosis inducing factor in a Bcl-2-dependent manner
Loss-of-function mutations in angiogenin (ANG) gene were discovered in amyotrophic lateral sclerosis (ALS) patients and ANG has been shown to prevent neuronal death both in vitro and in vivo. The neuro-protective activity of ANG was brought about partially by inhibiting stress-induced apoptosis. ANG...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3206144/ https://ncbi.nlm.nih.gov/pubmed/21678416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22881 |
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