Activation of Sirt1 by Resveratrol Inhibits TNF-α Induced Inflammation in Fibroblasts

Inflammation is one of main mechanisms of autoimmune disorders and a common feature of most diseases. Appropriate suppression of inflammation is a key resolution to treat the diseases. Sirtuin1 (Sirt1) has been shown to play a role in regulation of inflammation. Resveratrol, a potent Sirt1 activator...

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Autors principals: Zhu, Xiaoxia, Liu, Qiong, Wang, Meimei, Liang, Minrui, Yang, Xue, Xu, Xue, Zou, Hejian, Qiu, Jianhua
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206084/
https://ncbi.nlm.nih.gov/pubmed/22069489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027081
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