Genetic Basis for In Vivo Daptomycin Resistance in Enterococci

BACKGROUND: Daptomycin is a lipopeptide with bactericidal activity that acts on the cell membrane of enterococci and is often used off-label to treat patients infected with vancomycin-resistant enterococci. However, the emergence of resistance to daptomycin during therapy threatens its usefulness. M...

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Main Authors: Arias, Cesar A., Panesso, Diana, McGrath, Danielle M., Qin, Xiang, Mojica, Maria F., Miller, Corwin, Diaz, Lorena, Tran, Truc T., Rincon, Sandra, Barbu, E. Magda, Reyes, Jinnethe, Roh, Jung H., Lobos, Elizabeth, Sodergren, Erica, Pasqualini, Renata, Arap, Wadih, Quinn, John P., Shamoo, Yousif, Murray, Barbara E., Weinstock, George M.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205971/
https://ncbi.nlm.nih.gov/pubmed/21899450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1011138
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