Unique Gene Expression Profile Associated with an Early-Onset Multiple Endocrine Neoplasia (MEN1)-Associated Pituitary Adenoma

CONTEXT: Multiple endocrine neoplasia type 1 (MEN1) is caused by mutations in the menin (MEN1) gene. The mechanism(s) by which MEN1 mutations lead to pituitary tumor formation remain(s) unknown. OBJECTIVE: The aim of the study was to identify the pediatric MEN1-associated pituitary tumor transcripto...

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Detalhes bibliográficos
Main Authors: Farrell, William E., Azevedo, Monalisa F., Batista, Dalia L., Smith, Alastair, Bourdeau, Isabelle, Horvath, Anelia, Boguszewski, Margaret, Quezado, Martha, Stratakis, Constantine A.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
Assuntos:
JCEM Online: Advances in Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205896/
https://ncbi.nlm.nih.gov/pubmed/21917868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2011-1127
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