Opioid Receptor Blockade Improves Hypoglycemia-Associated Autonomic Failure in Type 1 Diabetes Mellitus

CONTEXT: Recurrent hypoglycemia induces hypoglycemia-associated autonomic failure (HAAF), characterized by deterioration in counterregulatory responses. Endogenous opioids may mediate the development of HAAF, and blockade of opioid receptors with naloxone prevented HAAF in nondiabetic subjects. OBJE...

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Autors principals: Vele, Septimiu, Milman, Sofiya, Shamoon, Harry, Gabriely, Ilan
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2011
Matèries:
Endocrine Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205891/
https://ncbi.nlm.nih.gov/pubmed/21917871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2011-1723
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