Opioid Receptor Blockade Improves Hypoglycemia-Associated Autonomic Failure in Type 1 Diabetes Mellitus

CONTEXT: Recurrent hypoglycemia induces hypoglycemia-associated autonomic failure (HAAF), characterized by deterioration in counterregulatory responses. Endogenous opioids may mediate the development of HAAF, and blockade of opioid receptors with naloxone prevented HAAF in nondiabetic subjects. OBJE...

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Hlavní autoři: Vele, Septimiu, Milman, Sofiya, Shamoon, Harry, Gabriely, Ilan
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2011
Témata:
Endocrine Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205891/
https://ncbi.nlm.nih.gov/pubmed/21917871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2011-1723
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