Opioid Receptor Blockade Improves Hypoglycemia-Associated Autonomic Failure in Type 1 Diabetes Mellitus

CONTEXT: Recurrent hypoglycemia induces hypoglycemia-associated autonomic failure (HAAF), characterized by deterioration in counterregulatory responses. Endogenous opioids may mediate the development of HAAF, and blockade of opioid receptors with naloxone prevented HAAF in nondiabetic subjects. OBJE...

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Detalhes bibliográficos
Main Authors: Vele, Septimiu, Milman, Sofiya, Shamoon, Harry, Gabriely, Ilan
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
Assuntos:
Endocrine Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205891/
https://ncbi.nlm.nih.gov/pubmed/21917871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2011-1723
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