l-DOPA-induced Dyskinesia is Associated with Regional Increase of Striatal Dynorphin Peptides as Elucidated by Imaging Mass Spectrometry

Opioid peptides are involved in various pathophysiological processes, including algesia, epilepsy, and drug dependence. A strong association between l-DOPA-induced dyskinesia (LID) and elevated prodynorphin mRNA levels has been established in both patients and in animal models of Parkinson's di...

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Hlavní autoři: Hanrieder, Jörg, Ljungdahl, Anna, Fälth, Maria, Mammo, Sofie Eriksson, Bergquist, Jonas, Andersson, Malin
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2011
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205869/
https://ncbi.nlm.nih.gov/pubmed/21737418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.009308
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