l-DOPA-induced Dyskinesia is Associated with Regional Increase of Striatal Dynorphin Peptides as Elucidated by Imaging Mass Spectrometry

Opioid peptides are involved in various pathophysiological processes, including algesia, epilepsy, and drug dependence. A strong association between l-DOPA-induced dyskinesia (LID) and elevated prodynorphin mRNA levels has been established in both patients and in animal models of Parkinson's di...

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Detalhes bibliográficos
Main Authors: Hanrieder, Jörg, Ljungdahl, Anna, Fälth, Maria, Mammo, Sofie Eriksson, Bergquist, Jonas, Andersson, Malin
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205869/
https://ncbi.nlm.nih.gov/pubmed/21737418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.009308
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