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Pancreatic β-cell Raf-1 is required for glucose tolerance, insulin secretion, and insulin 2 transcription
Regulation of glucose homeostasis by insulin depends on pancreatic β-cell growth, survival, and function. Raf-1 kinase is a major downstream target of several growth factors that promote proliferation and survival of many cell types, including the pancreatic β cells. We have previously reported that...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Federation of American Societies for Experimental Biology
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3205833/ https://ncbi.nlm.nih.gov/pubmed/21817126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-180349 |
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