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Systemic Adeno-Associated Virus-Mediated Gene Therapy Preserves Retinal Ganglion Cells and Visual Function in DBA/2J Glaucomatous Mice

A slow progressive death of neurons is the hallmark of neurodegenerative diseases, such as glaucoma. A therapeutic candidate, erythropoietin (EPO), has shown promise in many models of these diseases; however, it also causes polycythemia, a potentially lethal side effect. We have developed a novel mu...

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Détails bibliographiques
Auteurs principaux: Sullivan, Timothy A., Geisert, Eldon E., Hines-Beard, Jessica, Rex, Tonia S.
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205793/
https://ncbi.nlm.nih.gov/pubmed/21542676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2011.052
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