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Genome-scale phylogenetic function annotation of large and diverse protein families

The Statistical Inference of Function Through Evolutionary Relationships (SIFTER) framework uses a statistical graphical model that applies phylogenetic principles to automate precise protein function prediction. Here we present a revised approach (SIFTER version 2.0) that enables annotations on a g...

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Autori principali: Engelhardt, Barbara E., Jordan, Michael I., Srouji, John R., Brenner, Steven E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205580/
https://ncbi.nlm.nih.gov/pubmed/21784873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.104687.109
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