Phenotypic profiling of the human genome reveals gene products involved in plasma membrane targeting of SRC kinases

SRC proteins are non-receptor tyrosine kinases that play key roles in regulating signal transduction by a diverse set of cell surface receptors. They contain N-terminal SH4 domains that are modified by fatty acylation and are functioning as membrane anchors. Acylated SH4 domains are both necessary a...

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Detalhes bibliográficos
Main Authors: Ritzerfeld, Julia, Remmele, Steffen, Wang, Tao, Temmerman, Koen, Brügger, Britta, Wegehingel, Sabine, Tournaviti, Stella, Strating, Jeroen R.P.M., Wieland, Felix T., Neumann, Beate, Ellenberg, Jan, Lawerenz, Chris, Hesser, Jürgen, Erfle, Holger, Pepperkok, Rainer, Nickel, Walter
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
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Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205579/
https://ncbi.nlm.nih.gov/pubmed/21795383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.116087.110
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