Triglyceride Response to an Intensive Lifestyle Intervention Is Enhanced in Carriers of the GCKR Pro446Leu Polymorphism

CONTEXT: Glucokinase regulatory protein (GCKR) regulates the trafficking and enzymatic activity of hepatic glucokinase, the rate-limiting enzyme in glycogen synthesis and glycolysis. The intronic single-nucleotide polymorphism (SNP) rs780094 (intron 16) and the missense SNP rs1260326 (P446L) in the...

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Autori principali: Pollin, Toni I., Jablonski, Kathleen A., McAteer, Jarred B., Saxena, Richa, Kathiresan, Sekar, Kahn, Steven E., Goldberg, Ronald B., Altshuler, David, Florez, Jose C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2011
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Brief Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205512/
https://ncbi.nlm.nih.gov/pubmed/21525158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2010-2324
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