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Integrin α9β1-mediated cell migration in glioblastoma via SSAT and Kir4.2 potassium channel pathway
The α9β1 integrin accelerates cell migration through binding of the α9 cytoplasmic domain to SSAT, which catalyzes the catabolism of higher order polyamines, spermidine and spermine, to the lower order polyamine, putrescine. SSAT levels were downregulated at both the mRNA and protein levels by shRNA...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3205329/ https://ncbi.nlm.nih.gov/pubmed/21946432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2011.09.011 |
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