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Comparative effects of the 5'-triphosphates of 9-beta-(2'-azido-2'-deoxy-D-arabinofuranosyl)adenine and 9-beta-D-arabinofuranosyladenine on DNA polymerases from L1210 leukemia cells.

9-beta-(2'-Azido-2'-deoxy-D-arabiofuranosyl)adenine (arazide) causes greater and significantly more persistent inhibition of [3H]-thymidine incorporation into the DNA of neoplastic cells than the related agent 9-beta-D-arabinofuranosyladenine (araA). To elucidate the mechanism(s) responsib...

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Main Authors: Allaudeen, H S, Kozarich, J W, Sartorelli, A C
格式: Artigo
語言:Inglês
出版: 1982
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC320532/
https://ncbi.nlm.nih.gov/pubmed/6175955
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