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Comparative effects of the 5'-triphosphates of 9-beta-(2'-azido-2'-deoxy-D-arabinofuranosyl)adenine and 9-beta-D-arabinofuranosyladenine on DNA polymerases from L1210 leukemia cells.

9-beta-(2'-Azido-2'-deoxy-D-arabiofuranosyl)adenine (arazide) causes greater and significantly more persistent inhibition of [3H]-thymidine incorporation into the DNA of neoplastic cells than the related agent 9-beta-D-arabinofuranosyladenine (araA). To elucidate the mechanism(s) responsib...

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Udgivet i:Nucleic Acids Res
Main Authors: Allaudeen, H S, Kozarich, J W, Sartorelli, A C
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1982
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC320532/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6175955/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/10.4.1379
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