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Dysregulation of the unfolded protein response in db/db mice with diet induced steatohepatitis

In humans with non-alcoholic fatty liver, diabetes is associated with more advanced disease. We have previously shown that diabetic db/db mice are highly susceptible to methionine choline deficient diet (MCD) induced hepatic injury. Since activation of the unfolded protein response (UPR) is an impor...

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Detalhes bibliográficos
Main Authors: Rinella, Mary E., Siddiqui, M. Shaddab, Gardikiotes, Konstantina, Gottstein, Jeanne, Elias, Marc, Green, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205284/
https://ncbi.nlm.nih.gov/pubmed/21748768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24553
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