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Dysregulation of the unfolded protein response in db/db mice with diet induced steatohepatitis
In humans with non-alcoholic fatty liver, diabetes is associated with more advanced disease. We have previously shown that diabetic db/db mice are highly susceptible to methionine choline deficient diet (MCD) induced hepatic injury. Since activation of the unfolded protein response (UPR) is an impor...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3205284/ https://ncbi.nlm.nih.gov/pubmed/21748768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24553 |
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