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Upregulation of Hedgehog Pathway is Associated with Cellular Permissiveness for Hepatitis C Virus Replication

Studies of the Hepatitis C virus (HCV) life-cycle rely heavily upon Huh7.5 cells, but the reasons why these cells are exceptionally permissive for HCV replication are not clear. Based on recent clinical observations, we hypothesized that the Hedgehog (Hh) pathway, which has not been previously assoc...

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Detalhes bibliográficos
Main Authors: Choi, Steve S., Bradrick, Shelton, Qiang, Guan, Mostafavi, Anahita, Chaturvedi, Gaurav, Weinman, Steven A., Diehl, Anna Mae, Jhaveri, Ravi
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205266/
https://ncbi.nlm.nih.gov/pubmed/21793033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24576
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