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Differential Expression and Signaling Activation of Insulin Receptor Isoforms A and B: A Link between Breast Cancer and Diabetes?
We showed that when IGF-II is highly expressed in breast tissues and cell lines the IGF-1 receptor signaling pathway is highly activated. Since IGF-II activates the insulin receptor (INSR), we propose that the INSR signaling is also activated in this system. We examined the expression of both INSR i...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3205219/ https://ncbi.nlm.nih.gov/pubmed/21913804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08977194.2011.616200 |
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