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Multifunctional dendrimer/combretastatin A4 inclusion complexes enable in vitro targeted cancer therapy

BACKGROUND: We report here a unique approach to using multifunctional dendrimer/combretastatin A4 (CA4) inclusion complexes for targeted cancer therapeutics. METHODS: Amine-terminated generation 5 polyamidoamine dendrimers were first partially acetylated to neutralize a significant portion of the te...

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Detalhes bibliográficos
Main Authors: Zhang, Mengen, Guo, Rui, Wang, Yin, Cao, Xueyan, Shen, Mingwu, Shi, Xiangyang
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205130/
https://ncbi.nlm.nih.gov/pubmed/22072871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S24705
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