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Influence of dendrimer surface charge on the bioactivity of 2-methoxyestradiol complexed with dendrimers

We report the complexation of a potential anticancer agent 2-methoxyestradiol (2-ME) with generation 5 (G5) poly(amidoamine) dendrimers having different surface functional groups for therapeutic applications. The complexation experiment shows that approximately 6–8 drug molecules can be complexed wi...

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Detalhes bibliográficos
Main Authors: Shi, Xiangyang, Lee, Inhan, Chen, Xisui, Shen, Mingwu, Xiao, Shili, Zhu, Meifang, Baker, James R., Wang, Su He
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941193/
https://ncbi.nlm.nih.gov/pubmed/20852741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b925274f
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