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Association and Expression analyses with SNPs in TOMM40 in Alzheimer’s Disease

OBJECTIVES: Apolipoprotein E (APOE) is the most statistically significant genetic risk factor for late-onset Alzheimer’s disease (LOAD). The linkage disequilibrium pattern around the APOE gene has made it difficult to determine whether all of the association signal is derived from APOE or if there i...

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Autors principals: Cruchaga, Carlos, Nowotny, Petra, Kauwe, John S.K., Ridge, Perry G., Mayo, Kevin, Bertelsen, Sarah, Hinrichs, Anthony, Fagan, Anne M., Holtzman, David M., Morris, John C., Goate, Alison M.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204798/
https://ncbi.nlm.nih.gov/pubmed/21825236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneurol.2011.155
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