Neonatal Induction of Myelin-specific Th1/Th17 Immunity Does Not Result in Experimental Autoimmune Encephalomyelitis and Can Protect Against the Disease in Adulthood

The neonatal immune system is believed to be biased towards T helper type 2 (Th2) immunity, but under certain conditions neonates can also develop Th1 immune responses. Neonatal Th2 immunity to myelin antigens is not pathogenic and can prevent induction of experimental autoimmune encephalomyelitis (...

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Main Authors: Hofstetter, Harald H., Kovalovsky, Andra, Shive, Carey L., Lehmann, Paul V., Forsthuber, Thomas G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204791/
https://ncbi.nlm.nih.gov/pubmed/17482277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2007.04.001
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