Carcinoma mucins trigger reciprocal activation of platelets and neutrophils in a murine model of Trousseau syndrome

Trousseau syndrome is classically defined as migratory, heparin-sensitive but warfarin-resistant microthrombi in patients with occult, mucinous adenocarcinomas. Injecting carcinoma mucins into mice generates platelet-rich microthrombi dependent on P- and L-selectin but not thrombin. Heparin prevents...

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Главные авторы: Shao, Bojing, Wahrenbrock, Mark G., Yao, Longbiao, David, Tovo, Coughlin, Shaun R., Xia, Lijun, Varki, Ajit, McEver, Rodger P.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2011
Предметы:
Plenary Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204725/
https://ncbi.nlm.nih.gov/pubmed/21860019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-07-368514
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