Three different mutations in codon 61 of the human N-ras gene detected by synthetic oligonucleotide hybridization.

The activation of ras genes in naturally occurring tumors has, thus far, been found to be due to mutations in codon 12 or 61 resulting in single amino acid substitutions. We have used highly labeled synthetic oligonucleotides to detect mutations in these codons and to determine the exact position of...

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Bibliographic Details
Main Authors: Bos, J L, Verlaan-de Vries, M, Jansen, A M, Veeneman, G H, van Boom, J H, van der Eb, A J
Format: Artigo
Language:Inglês
Published: 1984
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC320445/
https://ncbi.nlm.nih.gov/pubmed/6595642
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