Alcohol disrupts endoplasmic reticulum function and protein secretion in hepatocytes

BACKGROUND: Many alcoholic patients have serum protein deficiency that contributes to their systemic problems. The unfolded protein response (UPR) is induced in response to disequilibrium in the protein folding capability of the endoplasmic reticulum (ER) and is implicated in hepatocyte lipid accumu...

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Detaylı Bibliyografya
Asıl Yazarlar: Howarth, Deanna L., Vacaru, Ana M., Tsedensodnom, Orkhontuya, Mormone, Elisabetta, Nieto, Natalia, Costantini, Lindsey M., Snapp, Erik L., Sadler, Kirsten C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204333/
https://ncbi.nlm.nih.gov/pubmed/21790674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2011.01602.x
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