Generation of a recombinant rabies Flury LEP virus carrying an additional G gene creates an improved seed virus for inactivated vaccine production

The rabies Flury Low Egg Passage virus (LEP) has been widely used as a seed virus to generate inactive vaccine. Here, we established a reverse genetic system for LEP and generated a recombinant LEP virus (rLEP-G) that carries two identical G genes. This recombinant virus showed similar properties to...

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Detalhes bibliográficos
Main Authors: Tao, Lihong, Ge, Jinying, Wang, Xijun, Wen, Zhiyuan, Zhai, Hongyue, Hua, Tao, Zhao, Bolin, Kong, Dongni, Yang, Chinglai, Bu, Zhigao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204297/
https://ncbi.nlm.nih.gov/pubmed/21943337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-8-454
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