Expression, localization and polymorphisms of the nuclear receptor PXR in Barrett's esophagus and esophageal adenocarcinoma

BACKGROUND: The continuous exposure of esophageal epithelium to refluxate may induce ectopic expression of bile-responsive genes and contribute to the development of Barrett's esophagus (BE) and esophageal adenocarcinoma. In normal physiology of the gut and liver, the nuclear receptor Pregnane...

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Main Authors: van de Winkel, Anouk, Menke, Vivianda, Capello, Astrid, Moons, Leon MG, Pot, Raymond GJ, van Dekken, Herman, Siersema, Peter D, Kusters, Johannes G, van der Laan, Luc JW, Kuipers, Ernst J
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204292/
https://ncbi.nlm.nih.gov/pubmed/21977915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-11-108
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