In vitro activities of novel 4-HPR derivatives on a panel of rhabdoid and other tumor cell lines

BACKGROUND: Rhabdoid tumors (RTs) are aggressive pediatric malignancies with poor prognosis. N-(4-hydroxy phenyl) retinamide (4-HPR or fenretinide) is a potential chemotherapeutic for RTs with activity correlated to its ability to down-modulate Cyclin D1. Previously, we synthesized novel halogen-sub...

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Bibliografische gegevens
Hoofdauteurs: Smith, Melissa E, Das, Bhaskar C, Kalpana, Ganjam V
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2011
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Primary Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204277/
https://ncbi.nlm.nih.gov/pubmed/21951911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-11-34
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