Terfenadine induces apoptosis and autophagy in melanoma cells through ROS-dependent and -independent mechanisms

Previously we found that terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca(2+) homeostasis. In this report, focusing our attention on the apoptotic mechanisms activated by terfenadine, we show that this drug can potentiall...

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Detalles Bibliográficos
Autores principales: Nicolau-Galmés, Francesca, Asumendi, Aintzane, Alonso-Tejerina, Erika, Pérez-Yarza, Gorka, Jangi, Shawkat-Muhialdin, Gardeazabal, Jesús, Arroyo-Berdugo, Yoana, Careaga, Jesús María, Díaz-Ramón, Jose Luís, Apraiz, Aintzane, Boyano, María D.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer US 2011
Materias:
Original Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204001/
https://ncbi.nlm.nih.gov/pubmed/21861192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-011-0640-y
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