Selective Over-Expression of Endothelin-1 in Endothelial Cells Exacerbates Inner Retinal Edema and Neuronal Death in Ischemic Retina

The level of endothelin-1 (ET-1), a potent vasoconstrictor, was associated with retinopathy under ischemia. The effects of endothelial endothelin-1 (ET-1) over-expression in a transgenic mouse model using Tie-1 promoter (TET-1 mice) on pathophysiological changes of retinal ischemia were investigated...

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Main Authors: Cheung, Simon S. F., Leung, Justin W. C., Lam, Amy K. M., Lam, Karen S. L., Chung, Stephen S. M., Lo, Amy C. Y., Chung, Sookja K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203861/
https://ncbi.nlm.nih.gov/pubmed/22053184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026184
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