mRNA expression levels and genetic status of genes involved in the EGFR and NF-κB pathways in metastatic non-small-cell lung cancer patients

BACKGROUND: Metastatic non-small-cell lung cancer (NSCLC) has a dismal prognosis. EGFR is overexpressed or mutated in a large proportion of cases. Downstream components of the EGFR pathway and crosstalk with the NF-κB pathway have not been examined at the clinical level. We explored the prognostic s...

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Autori principali: Santarpia, Mariacarmela, Magri, Ignacio, Sanchez-Ronco, Maria, Costa, Carlota, Molina-Vila, Miguel Angel, Gimenez-Capitan, Ana, Bertran-Alamillo, Jordi, Mayo, Clara, Benlloch, Susana, Viteri, Santiago, Gasco, Amaya, Mederos, Nuria, Carcereny, Enric, Taron, Miquel, Rosell, Rafael
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203857/
https://ncbi.nlm.nih.gov/pubmed/21951562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-163
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