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Tunnels modulate ligand flux in a heme nitric oxide/oxygen binding (H-NOX) domain
Interior topological features, such as pockets and channels, have evolved in proteins to regulate biological functions by facilitating the diffusion of biomolecules. Decades of research using the globins as model heme proteins have clearly highlighted the importance of gas pockets around the heme in...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3203760/ https://ncbi.nlm.nih.gov/pubmed/21997213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1114038108 |
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